Mouse Homeobox Protein Nkx-2.1, NKX2-1 ELISA Kit

SKU: E1426Mo

Size:96 Tests-1 Kit

Background:Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation (PubMed: 22955271). Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (PubMed: 22356123).

Research_area:Others

Applications:ELISA

Target_protein:NKX2-1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.033ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Homeobox Protein Nkx-2.1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P50220

MASS(Da):38,570

GeneID:21869

Synonyms:Homeobox protein Nkx-2.1;NKX 2 1;NKX2 1;NKX2-1;T/EBP;Thyroid nuclear factor 1;Thyroid transcription factor 1;Thyroid-specific enhancer-binding protein;TTF-1;

Gene names:NKX2-1

Standard solution:32ng/ml