Mouse High molecular weight Adiponectin,ADIPOQ ELISA KIT

SKU: E1647Mo

Size:96 Tests-1 Kit

Background:Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. {ECO:0000269|PubMed:11479627, ECO:0000269|PubMed:11479628, ECO:0000269|PubMed:12840063, ECO:0000269|PubMed:15734737, ECO:0000269|PubMed:15760892}.

Research_area:

Applications:ELISA

Target_protein:Adipoq

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.06mg/L

Detection range:0.1-30mg/L

Sample type:Serum, plasma or other biological fluids

Full product name:High molecular weight Adiponectin

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q60994

MASS(Da):26809

GeneID:11450

Synonyms:Adipoq Acdc Acrp30 Apm1

Gene names:Adipoq

Standard solution:32mg/L