Mouse Growth Differentiation Factor 15, GDF15 ELISA Kit

SKU: E0224Mo

Size:96 Tests-1 Kit

Background:Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed: 28953886, PubMed: 28846097, PubMed: 28846099, PubMed: 28572090, PubMed: 23468844, PubMed: 29046435). On hepatocytes, inhibits growth hormone signaling (PubMed: 28572090).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:GDF15

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:1.52ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Growth Differentiation Factor 15

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Z0J7

MASS(Da):33,225

GeneID:23886

Synonyms:GDF 15;GDF15;GDF-15;Growth/differentiation factor 15;Macrophage inhibitory cytokine 1;MIC-1

Gene names:GDF15

Standard solution:960ng/L