Mouse Ephrin Type-B Receptor 4, EPHB4 ELISA Kit

SKU: E2059Mo

Size:96 Tests-1 Kit

Background:Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells.

Research_area:Others

Applications:ELISA

Target_protein:EPHB4

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.55ng/L

Detection range:1-400ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Ephrin Type-B Receptor 4

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P54761

MASS(Da):108,848

GeneID:13846

Synonyms:Developmental kinase 2;EPHB 4;EPHB4;Ephrin type-B receptor 4;Hepatoma transmembrane kinase;mDK-2;Tyrosine kinase MYK-1

Gene names:EPHB4

Standard solution:480ng/L