Mouse E3 Ubiquitin-protein Ligase Smurf1, SMURF1 ELISA Kit

SKU: E2036Mo

Size:96 Tests-1 Kit

Background:E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway (By similarity). Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway (By similarity). Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA (By similarity). Promotes ubiquitination and subsequent proteasomal degradation of MAVS (PubMed: 23087404). Plays a role in dendrite formation by melanocytes (By similarity).

Research_area:Cell Biology

Applications:ELISA

Target_protein:SMURF1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:9.56ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:E3 Ubiquitin-Protein Ligase SMURF1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9CUN6

MASS(Da):83,356

GeneID:75788

Synonyms:E3 ubiquitin-protein ligase SMURF1;HECT-type E3 ubiquitin transferase SMURF1;SMAD ubiquitination regulatory factor 1;SMAD-specific E3 ubiquitin-protein ligase 1;SMURF 1;SMURF1

Gene names:SMURF1

Standard solution:4800ng/L