Mouse Dickkopf-4,DKK4 ELISA KIT

SKU: E1213Mo

Size:96 Tests-1 Kit

Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:Dkk4

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.08ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Dickkopf-4

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8VEJ3

MASS(Da):24261

GeneID:234130

Synonyms:Dkk4

Gene names:Dkk4

Standard solution:24ng/ml