Mouse CREB Regulated Transcription Coactivator 3,CRTC3 ELISA KIT

SKU: E1074Mo

Size:96 Tests-1 Kit

Background:Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites (PubMed:29211348, PubMed:30611118). Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated (PubMed:29211348). Acts independently of CREB1 'Ser-133' phosphorylation (By similarity). Enhances the interaction of CREB1 with TAF4 (By similarity). Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR (By similarity). Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells (By similarity). {ECO:0000250|UniProtKB:Q6UUV7, ECO:0000269|PubMed:29211348, ECO:0000269|PubMed:30611118}.

Research_area:

Applications:ELISA

Target_protein:Crtc3

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.11ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:CREB Regulated Transcription Coactivator 3

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q91X84

MASS(Da):67027

GeneID:70461

Synonyms:Crtc3 Torc3

Gene names:Crtc3

Standard solution:24ng/ml