Mouse Collectin-11, COLEC11 ELISA Kit

SKU: E1962Mo

Size:96 Tests-1 Kit

Background:Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding. Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis.

Research_area:Others

Applications:ELISA

Target_protein:COLEC11

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.22ng/mL

Detection range:0.5-200ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Collectin-11

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q3SXB8

MASS(Da):28,989

GeneID:71693

Synonyms:CL-K1;COLEC 11;COLEC11;Collectin kidney protein 1;Collectin-11

Gene names:COLEC11

Standard solution:240ng/mL