Mouse Cofilin-1, CFL1 ELISA Kit

SKU: E1949Mo

Size:96 Tests-1 Kit

Background:Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed: 11809832). In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed: 25208553). Required for the centralization of the mitotic spindle and symmetric division of zygotes (PubMed: 25208553). Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (By similarity). Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (By similarity). Required for neural tube morphogenesis and neural crest cell migration (PubMed: 15649$475.00|$350.00).

Research_area:Others

Applications:ELISA

Target_protein:CFL1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:8.05ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cofilin-1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P18760

MASS(Da):18,560

GeneID:12631

Synonyms:CFL 1;CFL1;Cofilin, non-muscle isoform;Cofilin-1

Gene names:CFL1

Standard solution:3200ng/L