Mouse CLEC7A ELISA Kit PicoKine®

SKU: EK1923

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Clec7a

Specificity: Natural and recombinant mouse CLEC7A

Background: C-type lectin domain family 7 member A or Dectin-1 is a protein that in humans is encoded by the CLEC7A gene. This gene is mapped to 6; 6 F3. CLEC7A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with a partial immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor for a variety of β-1,3-linked and β-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Expression is found on myeloid dendritic cells, monocytes, macrophages and B cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Immunogen: Expression system for standard: NS0; Immunogen sequence: G71-L244

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Reference:

Uniprot ID: Q6QLQ4

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 56644

Protein Name: C-type lectin domain family 7 member A

Gene Full Name: C-type lectin domain family 7, member a

Synonyms: CLEC7A; BGR; CLECSF12; DECTIN1; UNQ539/PRO1082; C-type lectin domain family 7 member A; Beta-glucan receptor; C-type lectin superfamily member 12; Dendritic cell-associated C-type lectin 1; DC-associated C-type lectin 1; Dectin-1; CD369; CANDF4; SCARE2; C-type lectin domain containing 7A