Mouse Cd82 Antigen, CD82 ELISA Kit

SKU: E1922Mo

Size:96 Tests-1 Kit

Background:CD82 (Cluster of Differentiation 82), or KAI1, is a human protein encoded by the CD82 gene. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the tetraspanin/transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research_area:Immunology; Epigenetics and Nuclear Signaling; Cancer

Applications:ELISA

Target_protein:CD82

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:1.55ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:CD82 antigen

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P40237

MASS(Da):29,629

GeneID:12521

Synonyms:AL023070;C33;C33 antigen;CD antigen CD82;CD82;CD82 antigen;IA4;Inducible membrane protein R2;Ka;Kai1;Metastasis suppressor Kangai-1 homolog;Tsp;Tspan27;

Gene names:Cd82

Standard solution:960ng/L