Mouse CD30/TNFRSF8 ELISA Kit PicoKine®

SKU: EK0570

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: TNFRSF8

Specificity: Natural and recombinant mouse CD30

Background: CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. This gene is mapped to 1p36.22. CD30 is expressed in embryonal carcinoma but not in seminoma and is thus a useful marker in distinguishing between these germ cell tumors. CD30 mast cell activation represents an IgE-independent activation pathway, which is important for understanding cutaneous inflammation associated with mast cells. In addition to those, CD30 is also associated with anaplastic large cell lymphoma.

Immunogen: Expression system for standard: NS0; Immunogen sequence: F19-T281

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Reference:

Uniprot ID: Q60846

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 21941

Protein Name: Tumor necrosis factor receptor superfamily member 8

Gene Full Name: tumor necrosis factor receptor superfamily, member 8

Synonyms: CD30; CD30L receptor; D1S166E; Ki 1; Ki 1 antigen; TNFRSF8