Mouse Cd2-associated Protein, CD2AP ELISA Kit

SKU: E1734Mo

Size:96 Tests-1 Kit

Background:Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (By similarity). In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation (By similarity). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (PubMed: 9741631). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus (PubMed: 10514378). Also required for cytokinesis. Plays a role in epithelial cell junctions formation (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:CD2AP

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:5.13ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cd2-Associated Protein

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9JLQ0

MASS(Da):70,450

GeneID:12488

Synonyms:CD2AP;CD2-associated protein;Mesenchyme-to-epithelium transition protein with SH3 domains 1;METS-1

Gene names:CD2AP

Standard solution:2400ng/L