Mouse Cadherin-2, CDH2 ELISA Kit

SKU: E1892Mo

Size:96 Tests-1 Kit

Background:Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell (PubMed: 2762814, PubMed: 11433297, PubMed: 17988630, PubMed: 9655503, PubMed: 25253890). Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence (PubMed: 24952463). Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (PubMed: 26750727). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:CDH2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:14.35ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cadherin-2

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P15116

MASS(Da):99,796

GeneID:12558

Synonyms:Cadherin-2;CD antigen CD325;CDH 2;CDH2;N-cadherin;Neural cadherin

Gene names:CDH2

Standard solution:9600ng/L