Mouse Basigin, BSG ELISA Kit

SKU: E1870Mo

Size:96 Tests-1 Kit

Background:[Isoform 1]: Essential for normal retinal maturation and development (PubMed: 10967074, PubMed: 11273674, PubMed: 11853760). Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors (PubMed: 25957687). In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors (PubMed: 25957687). [Isoform 2]: Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells (By similarity). Plays an important role in targeting the monocarboxylate transporters SLC16A1/GLUT1, SLC16A3 and SLC16A8 to the plasma membrane (PubMed: 12601063). Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling (By similarity). Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA and KDR/VEGFR2 in endothelial cells (By similarity). Plays an important role in spermatogenesis; mediates interactions between germ cells and Sertoli cell and is essential for the development/differentiation of germ cells to round spermatids (PubMed: 23727514, PubMed: 11882021).

Research_area:Immunology; Signal Transduction; Neuroscience; Cancer

Applications:ELISA

Target_protein:BSG

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:9.29ng/L

Detection range:20-7000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Basigin

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P18572

MASS(Da):42,445

GeneID:12215

Synonyms:5f7;Basic immunoglobulin superfamily;Basigin;BSG;CD antigen CD147;CD147;EMMPRIN;HT7 antigen;M6;Membrane glycoprotein gp42;OK;TCSF

Gene names:BSG

Standard solution:8000ng/L