Mouse Autophagy Related Protein 4B, ATG4B ELISA Kit

SKU: E2636Mo

Size:96 Tests-1 Kit

Background:Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms (By similarity).

Research_area:Cancer

Applications:ELISA

Target_protein:ATG4B

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.024ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Autophagy Related Protein 4B

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8BGE6

MASS(Da):44,375

GeneID:66615

Synonyms:ATG 4B;ATG4B;AUT-like 1 cysteine endopeptidase;Autophagin-1;Autophagy-related cysteine endopeptidase 1;Autophagy-related protein 4 homolog B;Cysteine protease ATG4B

Gene names:ATG4B

Standard solution:24ng/ml