Mouse Autophagy related protein 14,ATG14 ELISA KIT

SKU: E2646Mo

Size:96 Tests-1 Kit

Background:Required for both basal and inducible autophagy (PubMed:19270696, PubMed:19270693). Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (By similarity). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:19270693). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (By similarity). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (By similarity). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation of PIK3C3 by AMPK (PubMed:23332761). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (By similarity). Modulates the hepatic lipid metabolism (PubMed:22992773). {ECO:0000250|UniProtKB:Q6ZNE5, ECO:0000269|PubMed:19270693, ECO:0000269|PubMed:19270696, ECO:0000269|PubMed:22992773, ECO:0000269|PubMed:23332761}.

Research_area:

Applications:ELISA

Target_protein:Atg14

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:4.88ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Autophagy related protein 14

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8CDJ3

MASS(Da):55388

GeneID:100504663

Synonyms:Atg14 Atg14L D14Ertd436e Kiaa0831

Gene names:Atg14

Standard solution:2400ng/L