Mouse Apelin receptor,APLNR ELISA KIT

SKU: E1303Mo

Size:96 Tests-1 Kit

Background:Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone (PubMed:28854362, PubMed:28890073, PubMed:28663440). May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis (By similarity). Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development (PubMed:28890073). Plays also a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility and heart failure (PubMed:28371822). {ECO:0000250|UniProtKB:P79960, ECO:0000250|UniProtKB:Q7SZP9, ECO:0000269|PubMed:28371822, ECO:0000269|PubMed:28663440, ECO:0000269|PubMed:28854362, ECO:0000269|PubMed:28890073}.

Research_area:

Applications:ELISA

Target_protein:Aplnr

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.18ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Apelin receptor

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9WV08

MASS(Da):42266

GeneID:23796

Synonyms:Aplnr Agtrl1 Apj

Gene names:Aplnr

Standard solution:48ng/ml