Mouse Agouti-signaling Protein, ASIP ELISA Kit

SKU: E1826Mo

Size:96 Tests-1 Kit

Background:Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). Causes hair follicle melanocytes to synthesize phaeomelanin instead of black or brown pigment eumelanin and produces hairs with a subapical yellow band on an otherwise black or brown background when expressed during the mid-portion of hair growth.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:ASIP

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:9.72ng/L

Detection range:20-6000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Agouti-signaling protein

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q03288

MASS(Da):14,313

GeneID:50518

Synonyms:A;ago;Agouti coat color protein;Agouti switch protein;Agouti-signaling protein;As;ASIP;ASP

Gene names:Asip

Standard solution:6400ng/L