MKRN1 Antibody, FITC conjugated - Cat. #: CSB-PA883390LC01HU

SKU: CSB-PA883390LC01HU

Size :50ug

Clone Number:

Aliases:E3 ubiquitin-protein ligase makorin-1 antibody; FLJ21334 antibody; HGNC:7112 antibody; Makorin antibody; Makorin ring finger protein 1 antibody; MKRN 1 antibody; mkrn1 antibody; MKRN1_HUMAN antibody; OTTHUMP00000212117 antibody; OTTHUMP00000212118 antibody; OTTHUMP00000212121 antibody; OTTHUMP00000212124 antibody; Ring finger protein 1 antibody; RING finger protein 61 antibody; RNF61 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UHC7

Immunogen:Recombinant Human E3 ubiquitin-protein ligase makorin-1 protein (109-209AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MKRN1

Research Areas:Epigenetics and Nuclear Signaling; Cell biology