MIOS Antibody, Biotin conjugated - Cat. #: CSB-PA865167LD01HU

SKU: CSB-PA865167LD01HU

Size :50ul

Clone Number:

Aliases:MIOS antibody; GATOR complex protein MIOS antibody; Missing oocyte meiosis regulator homolog antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NXC5

Immunogen:Recombinant Human GATOR complex protein MIOS protein (1-237AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MIOS

Research Areas:Cell Biology