MCTS1 Polyclonal Antibody

SKU: E-AB-15193

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: MCTS1

Target Synonym: FLJ39637;Malignant T cell-amplified sequence 1;MCT 1;MCT-1;MCT1;MCTS 1;MCTS1;MCTS1;Multiple copies T cell malignancies 1;Multiple copies T cell malignancies;Multiple copies T-cell malignancies;Oncogene MCT 1;Oncogene MCT1

Research Areas: Cancer

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9ULC4

Accession:

Background: MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.

Concentration: 0.2 mg/mL

Immunogen: Recombinant protein of human MCTS1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:200-1:1000;IHC 1:100-1:300

Calculated MW: 21kDa

ObservedMW: