MCTS1 Antibody - Cat. #: CSB-PA200543

SKU: CSB-PA200543

Size :50ul

Clone Number:

Aliases:FLJ39637 antibody; Malignant T cell amplified sequence 1 antibody; Malignant T cell-amplified sequence 1 antibody; MCT 1 antibody; MCT-1 antibody; MCT1 antibody; MCTS 1 antibody; MCTS1 antibody; MCTS1_HUMAN antibody; Multiple copies T cell malignancies 1 antibody; Multiple copies T cell malignancies antibody; Multiple copies T-cell malignancies antibody; Oncogene MCT 1 antibody; Oncogene MCT1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9ULC4

Immunogen:Fusion protein of Human MCTS1

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:100-1:300

Background:MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MCTS1

Research Areas:Cancer