MCM7 Polyclonal Antibody

SKU: E-AB-40231

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: MCM7

Target Synonym: CDABP0042;CDC 47;CDC47;CDC47 homolog;Cdc47; S. cerevisiae; homolog of;DNA replication licensing factor MCM7;Homolog of S. cerevisiae Cdc47;MCM 2;MCM 7;MCM2;MCM2; formerly;Mcm7;MCM7 minichromosome maintenance deficient 7;MCM7_HUMAN;Minichromosome Maintainence 7;Minichromosome maintainence; S. cerevisiae; homolog of;Minichromosome maintenance complex component 7;Minichromosome maintenance deficient 7;Minichromosome maintenance protein 7;P1.1 MCM3;P1.1-MCM3;P1CDC47;P85MCM;PNAS 146;PNAS146;PPP1R104;Protein phosphatase 1; regulatory subunit 104

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P33993

Accession:

Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Concentration: 1 mg/mL

Immunogen: Recombinant Human DNA replication licensing factor MCM7 protien

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: