MCM6 Polyclonal Antibody

SKU: E-AB-10451

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:MCM6

Target Synonym:DNA replication licensing factor MCM6;MCG40308;Mcm6;MCM6 minichromosome maintenance deficient 6 (MIS5 homolog;S. pombe);MCM6 minichromosome maintenance deficient 6;MCM6;Minichromosome maintenance complex component 6;Minichromosome maintenance deficient (mis5 S. pombe) 6;Minichromosome maintenance deficient 6 homolog;Minichromosome maintenance protein 6;Mis5;MIS5 homolog;p105MCM

Research Areas:Cancer;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q14566

Accession:

Background:The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

Concentration:0.6 mg/mL

Immunogen:Recombinant protein of human MCM6

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW:93kDa

ObservedMW: