MAML1 Antibody, HRP conjugated - Cat. #: CSB-PA838784LB01HU

SKU: CSB-PA838784LB01HU

Size :50ug

Clone Number:

Aliases:Mam-1 antibody; Mam1 antibody; MAML 1 antibody; Maml1 antibody; MAML1_HUMAN antibody; Mastermind like 1 antibody; Mastermind-like protein 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q92585

Immunogen:Recombinant Human Mastermind-like protein 1 protein (1-45AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MAML1

Research Areas:Stem cells