MAJIN Antibody - Cat. #: CSB-PA659444LA01HU

SKU: CSB-PA659444LA01HU

Size :50ug

Clone Number:

Aliases:MAJIN antibody; C11orf85Membrane-anchored junction protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q3KP22

Immunogen:Recombinant Human Membrane-anchored junction protein (1-216AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the complex, MAJIN acts as the anchoring subunit to the nucleus inner membrane. MAJIN shows DNA-binding activity, possibly for the stabilization of telomere attachment on the nucleus inner membrane.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MAJIN

Research Areas:Cell biology