LYVE1 Antibody - Cat. #: CSB-PA566878

SKU: CSB-PA566878

Size :100ul

Clone Number:

Aliases:Cell surface retention sequence-binding protein 1 antibody; CRSBP 1 antibody; CRSBP-1 antibody; CRSBP1 antibody; extracellular link domain containing 1 antibody; extracellular link domain-containing 1 antibody; Extracellular link domain-containing protein 1 antibody; HAR antibody; Hyaluronic acid receptor antibody; Lymphatic endothelium specific hyaluronan receptor antibody; lymphatic vessel endothelial hyaluronan receptor 1 antibody; Lymphatic vessel endothelial hyaluronic acid receptor 1 antibody; LYVE 1 antibody; LYVE-1 antibody; LYVE1 antibody; LYVE1_HUMAN antibody; XLKD1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y5Y7

Immunogen:Peptide sequence around aa.271~275 (K-N-Q-Q-K) derived from Human Lymphatic vessel endothelial hyaluronic acid receptor 1.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Heindl LM, et al. (2010) Ophthalmology.117(2):334-42.
He P et al.(2006) Lin Chuang Er Bi Yan Hou Ke Za Zhi.20(18):828-30, 833.
Lim HY,et al. (2009) Am J Pathol.175(3):1328-37.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LYVE1

Research Areas:Cardiovascular