LILRB2 Monoclonal Antibody

SKU: BT-MCA2784

Size:100μL

Background:This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Research_area:Immunology

Target_protein:LILRB2

applications:WB, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:2G7E11

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:LILRB2

Immunogen:Purified recombinant fragment of human LILRB2 (AA: 51-184) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):65kDa

UniProt accession:Q8N423

Synonyms:ILT4, LIR2, CD85D, ILT-4, LIR-2, MIR10, MIR-10

GeneID:10288