LCP1(Phospho-Tyr28) Rabbit Polyclonal Antibody

SKU: BT-AP03394

Size:100μL

Background:Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans| two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages| while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts| endothelial cells| epithelial cells| melanocytes| etc.). However| L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.

Research_area:Cancer; Signal transduction ; Epigenetics and nuclear signaling

Target_protein:LCP1

applications:WB

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:LCP1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P13796; Mouse: Q61233

Synonyms:LCP1 ;Tyr28; Plastin-2; L-plastin; LC64P; Lymphocyte cytosolic protein 1; LCP-1

GeneID:Human: 3936; Mouse: 18826