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GeneBio Systems

Lamin B1 Mouse mAb

Lamin B1 Mouse mAb

SKU:EM1035

Regular price £281.00 GBP
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Size: 100μL

Source:Mouse

Applications:WB, IP

Reactivity:Human, Rat, Mouse

Dilution:WB 1:2,000-5,000 IP 1:200

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):68kDa

Human_gene_id:4001

Human_swiss_prot_no:P20700

Subcellular_location:Mitochondrion inner membrane

Other_name:ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218

Background:The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

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