(KO Validated) IGF1R Polyclonal Antibody

SKU: E-AB-68249

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:IGF1R

Target Synonym:IGF1R;CD221;IGFIR;IGFR;JTK13

Research Areas:Cancer;Developmental Biology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P08069

Accession:

Background:This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Concentration:1 mg/mL

Immunogen:A synthetic peptide of human IGF1R

Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:154kDa

ObservedMW:100KDa