KLF4 Antibody - Cat. #: CSB-PA012394DSR2HU

SKU: CSB-PA012394DSR2HU

Size :50ul

Clone Number:

Aliases:Endothelial Kruppel like zinc finger protein antibody; Epithelial zinc finger protein EZF antibody; EZF antibody; GKLF antibody; gut Kruppel-like factor antibody; Gut-enriched krueppel-like factor antibody; KLF antibody; KLF4 antibody; KLF4_HUMAN antibody; Krueppel-like factor 4 antibody; Kruppel like factor 4 (Epithelial zinc finger protein EZF) (Gut enriched Krueppel like factor) antibody; Kruppel like factor 4 (gut) antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43474

Immunogen:Recombinant Human Krueppel-like factor 4 protein (30-230AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background:Transcription factor; can act both as activator and as repressor. Binds the 5\\\'-CACCC-3\\\' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KLF4

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Developmental biology; Stem cells