KLF1 Polyclonal Antibody

SKU: E-AB-19799

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: KLF1

Target Synonym: CDAN4;EKLF;EKLF PEN;Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor);Erythroid krueppel-like transcription factor;Erythroid Kruppel like factor;Erythroid specific transcription factor EKLF;HBFQTL6;Human erythroid-specific transcription factor EKLF mRNA complete cds;INLU;Klf1;KLF1;Krueppel-like factor 1;Kruppel like factor 1 (erythroid)

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q13351

Accession:

Background: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.

Concentration: 0.96 mg/mL

Immunogen: Synthetic peptide of human KLF1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:100

Calculated MW:

ObservedMW: