KIR3.2 rabbit pAb

SKU: ES15302

Size: 100μL

Source:Rabbit

Applications:IHC;IF;WB

Reactivity:Human; Mouse; Rat

Dilution:IHC-p 1:50-200, WB 1:500-2000

Immunogen:Synthesized peptide derived from human KIR3.2

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):48kD

Human_gene_id:3763

Human_swiss_prot_no:P48051

Subcellular_location:Membrane; Multi-pass membrane protein.

Other_name:G protein-activated inward rectifier potassium channel 2 (GIRK-2;BIR1;Inward rectifier K(+) channel Kir3.2;KATP-2;Potassium channel, inwardly rectifying subfamily J member 6)

Background:This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015],