GeneBio Systems
KIF7 Monoclonal Antibody
KIF7 Monoclonal Antibody
SKU:E-AB-22026
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Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Monoclonal Antibodies
Abbreviation: Kif 7
Target Synonym: EQYK340;kif7;KIF7;kinesin family member 7;kinesin like protein KIF7;Kinesin-like protein kif7;UNQ340
Research Areas: Signal Transduction;Stem Cells
Conjugation: Unconjugated
Host: Mouse
Species reactivity: Human;Mouse;Rat
Application: IHC-p;IF
Isotype: IgG
Clonality: Monoclonal
Clone NO.: Clone:3I4
UNIProt ID: Q2M1P5
Accession:
Background: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.
Concentration: 1 mg/mL
Immunogen: Synthetic Peptide
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification method: Protein A purification
Dilution: IHC 1:100-1:300;IF 1:50-200
Calculated MW:
ObservedMW:
