KHSRP antibody , Cat. # FNab04525

SKU: FNab04525

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Binds to the dendritic targeting element and may play a role in mRNA trafficking(By similarity). Part of a ternary complex that binds to the downstream control sequence(DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element(FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements(AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

Immunogen:KH-type splicing regulatory protein

Synonyms:FBP2, FUBP2, FUSE binding protein 2, KHSRP, KSRP, p75

Observed MW:75 kDa

Uniprot ID:Q92945

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID:8570

Research Area:Epigenetics, Metabolism