KDM5B Polyclonal Antibody

SKU: E-AB-13360

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: KDM5B

Target Synonym: Cancer/testis antigen 31;CT31;Histone demethylase JARID1B;JARID1B;Jumonji AT rich interactive domain 1B;Jumonji/ARID domain-containing protein 1B;Kdm5b;KDM5B;Lysine (K) specific demethylase 5B;Lysine demethylase 5B;Lysine specific demethylase 5B;Lysine-specific demethylase 5B;PLU-1;PLU1;PPP1R98;Protein phosphatase 1 regulatory subunit 98;PUT1;putative DNA/chromatin binding motif;RBBP2H1A;RBP2 like;RBP2-H1;Retinoblastoma-binding protein 2 homolog 1;Retinoblastoma-binding protein 2 homolog 1A

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9UGL1

Accession:

Background: PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.

Concentration: 1.5 mg/mL

Immunogen: Synthetic peptide of human KDM5B

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: