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Gene Bio Systems

KDM4B Antibody - Cat. #: CSB-PA991708

KDM4B Antibody - Cat. #: CSB-PA991708

CSB-PA991708

£288.00 GBP
£288.00 GBP
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Size :50ul

Clone Number:

Aliases:JHDM3B antibody; JmjC domain-containing histone demethylation protein 3B antibody; JMJD2B antibody; Jumonji domain containing 2B antibody; Jumonji domain containing protein 2B antibody; Jumonji domain-containing protein 2B antibody; Kdm4b antibody; KDM4B_HUMAN antibody; KIAA0876 antibody; Lysine (K) specific demethylase 4B antibody; Lysine demethylase 4B antibody; Lysine-specific demethylase 4B antibody; TDRD14B antibody; Tudor domain containing 14B antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O94953

Immunogen:Synthetic peptide of Human KDM4B

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:JMJD2B (JmjC domain-containing histone demethylation protein 3A) is a 1,064 amino acid protein encoded by the human gene JMJD2B. JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers and two Tudor domains. The two Tudor domains recognize and bind methylated histones and have an interdigitated structure; the unusual fold is required for its ability to bind methylated histone tails. JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, thereby playing a role in histone code. It does not demethylate Histone H3 Lys 4, H3 Lys 27, H3 Lys 36 or H4 Lys 20, however, and is only able to demethylate trimethylated H3 Lys-9 and has weaker activity than JMJD2A, JMJD2C and JMJD2D. JMJD2B demethyl-ation of Lysine residues will generate formaldehyde and succinate. JMJD2B is a ubiquitously expressed nuclear protein.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KDM4B

Research Areas:Epigenetics and Nuclear Signaling

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