KCNN4 (SK4) rabbit pAb

SKU: ES20693

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF

Reactivity:Human;Rat;Mouse

Dilution:WB 1:1000-2000, IHC 1:50-100

Immunogen:Synthetic Peptide of KCNN4 (SK4) AA range: 177-227

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):50kD

Human_gene_id:3783

Human_swiss_prot_no:O15554

Subcellular_location:Cell membrane ; Multi-pass membrane protein .

Other_name:KCNN4; IK1; IKCA1; KCA4; SK4; Intermediate conductance calcium-activated potassium channel protein 4; SK4; SKCa 4; SKCa4; IKCa1; IK1; KCa3.1; KCa4; Putative Gardos channel

Background:potassium calcium-activated channel subfamily N member 4(KCNN4) Homo sapiens The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008],