KCNH3 rabbit pAb

SKU: ES5342

Size: 100μL

Source:Rabbit

Applications:WB;IHC

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000;IHC-p 1:50-300

Immunogen:Synthesized peptide derived from KCNH3 . at AA range: 470-550

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):120kD

Human_gene_id:23416

Human_swiss_prot_no:Q9ULD8

Subcellular_location:Membrane; Multi-pass membrane protein.

Other_name:KCNH3; KIAA1282; Potassium voltage-gated channel subfamily H member 3; Brain-specific eag-like channel 1; BEC1; Ether-a-go-go-like potassium channel 2; ELK channel 2; ELK2; Voltage-gated potassium channel subunit Kv12.2

Background:The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015],