KChIP1 Rabbit pAb

SKU: EA304

Size: 100μL

Source:Rabbit

Applications:IHC

Reactivity:Human, Mouse

Dilution:IHC 1:100-200

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Polyclonal

Isotype:IgG

Concentration:1mg/mL

Observed_band(KD):30kDa

Human_gene_id:30820

Human_swiss_prot_no:Q9NZI2

Subcellular_location:Cell membrane, Cell projection, Cytoplasm, Membrane

Other_name:KCNIP1,MGC9,MGC95,A type potassium channel modulatory protein 1

Background:Human K(v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K(+) channels, GABAergic transmission and cell death.