KCC2B Polyclonal Antibody

SKU: BT-AP10623

Size:100μL

Background:The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants.

Research_area:Cell biology; Epigenetics and nuclear signaling; Neuroscience; Signal transduction

Target_protein:CAMK2B

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Calcium/calmodulin-dependent protein kinase type II subunit beta

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q13554; Mouse: P28652; Rat: P08413

Synonyms:Calcium/calmodulin-dependent protein kinase type II subunit beta ;CaM kinase II subunit beta;CaMK-II subunit beta;EC 2.7.11.17

GeneID:Human: 816