KAT6B Polyclonal Antibody

SKU: BT-AP10619

Size:100μL

Background:The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.

Research_area:Epigenetics and nuclear signaling

Target_protein:KAT6B

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Histone acetyltransferase KAT6B

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q8WYB5; Mouse: Q8BRB7

Synonyms:Histone acetyltransferase KAT6B ;EC 2.3.1.48;Histone acetyltransferase MOZ2;MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4;MYST-4;Monocytic leukemia zinc finger protein-related factor

GeneID:Human: 23522