KAT2B Antibody - Cat. #: CSB-PA835706LA01HU

SKU: CSB-PA835706LA01HU

Size :50ug

Clone Number:

Aliases:CAF antibody; CREBBP associated factor antibody; GCN5 antibody; GCN5L antibody; GCN5L1 antibody; Histone acetylase PCAF antibody; Histone acetyltransferase KAT2B antibody; Histone acetyltransferase PCAF antibody; K(lysine) acetyltransferase 2B antibody; KAT2B antibody; KAT2B_HUMAN antibody; Lysine acetyltransferase 2B antibody; P antibody; P/CAF antibody; p300/CBP associated factor antibody; P300/CBP-associated factor antibody; Pcaf antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q92831

Immunogen:Recombinant Human Histone acetyltransferase KAT2B protein (767-832AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat\'s transactivating activity and may help inducing chromatin remodeling of proviral genes. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KAT2B

Research Areas:Epigenetics and Nuclear Signaling; Cell biology; Microbiology