ITGA5 Antibody, Biotin conjugated - Cat. #: CSB-PA011868LD01HU

SKU: CSB-PA011868LD01HU

Size :50ug

Clone Number:

Aliases:CD49 antigen-like family member E antibody; CD49e antibody; Fibronectin receptor subunit alpha antibody; Fibronectin receptor; alpha subunit antibody; FNRA antibody; Integrin alpha 5 (fibronectin receptor alpha) antibody; Integrin alpha-5 antibody; Integrin alpha-5 light chain antibody; Integrin alpha-F antibody; Integrin; alpha 5 (fibronectin receptor; alpha polypeptide) antibody; ITA5_HUMAN antibody; Itga5 antibody; Very late activation protein 5; alpha subunit antibody; VLA-5 antibody; VLA5 antibody; VLA5A antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P08648

Immunogen:Recombinant Human Integrin alpha-5 protein (220-472AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ITGA5

Research Areas:Signal transduction; Stem cells