ITCH/AIP4 Monoclonal Antibody

SKU: AN200064P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:ITCH

Target Synonym:AIF;AIP;NAPP;ITCH;ADMFD;AIF4;AIP4;NAPP1;dJ468O1.1

Research Areas:Cell Biology

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM;ICC/IF

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:5D10

UNIProt ID:Q96J02

Accession:

Background:This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E1 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant Human ITCH / AIP4 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:ICC/IF 1:20-1:100;FCM 1:25-1:100;

Calculated MW:

ObservedMW: