Isovaleryl-CoA dehydrogenase/IVD Monoclonal Antibody

SKU: AN200143P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:IVD

Target Synonym:ACAD;IVD;ACAD2;FLJ12715;FLJ34849;Isovaleryl CoA dehydrogenase;Isovaleryl Coenzyme A dehydrogenase;Isovaleryl-CoA dehydrogenase;mitochondrial

Research Areas:Signal Transduction;Metabolism

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB;FCM;ICC/IF;IP

Isotype:IgG2b

Clonality:Monoclonal

Clone NO.:13B6

UNIProt ID:P26440

Accession:

Background:Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant Human Isovaleryl-CoA dehydrogenase / IVD protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:1000;FCM 1:100-1:500;ICC/IF 1:100-1:500;IP 0.1-0.5 μL/mg of lysate

Calculated MW:47 kDa

ObservedMW:40 kDa