IRF4 Antibody - Cat. #: CSB-PA250376

SKU: CSB-PA250376

Size :100ul

Clone Number:

Aliases:Interferon regulatory factor 4 antibody; IRF 4 antibody; IRF-4 antibody; Irf4 antibody; IRF4_HUMAN antibody; LSIRF antibody; Lymphocyte specific interferon regulatory factor antibody; Lymphocyte specific IRF antibody; Lymphocyte-specific interferon regulatory factor antibody; Multiple myeloma oncogene 1 antibody; MUM 1 antibody; MUM1 antibody; NF EM5 antibody; NF-EM5 antibody; NFEM5 antibody; PU.1 interaction partner antibody; Sfpi1/PU.1 interaction partner antibody; Transcriptional activator PIP antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15306

Immunogen:Synthesized peptide derived from internal of Human IRF4.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes By similarity.

Grossman A., Genomics 37:229-233(1996).
Iida S., Nat. Genet. 17:226-230(1997).
Mungall A.J., Nature 425:805-811(2003).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IRF4

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Tags & Cell Markers