IRF4 Antibody - Cat. #: CSB-PA011819ESR2HU

SKU: CSB-PA011819ESR2HU

Size :50ul

Clone Number:

Aliases:Interferon regulatory factor 4 antibody; IRF 4 antibody; IRF-4 antibody; Irf4 antibody; IRF4_HUMAN antibody; LSIRF antibody; Lymphocyte specific interferon regulatory factor antibody; Lymphocyte specific IRF antibody; Lymphocyte-specific interferon regulatory factor antibody; Multiple myeloma oncogene 1 antibody; MUM 1 antibody; MUM1 antibody; NF EM5 antibody; NF-EM5 antibody; NFEM5 antibody; PU.1 interaction partner antibody; Sfpi1/PU.1 interaction partner antibody; Transcriptional activator PIP antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15306

Immunogen:Recombinant Human Interferon regulatory factor 4 protein (180-451AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\\\'-TGAnTCA/GAAA-3\\\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IRF4

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Tags & Cell Markers